Barnacles Inspired Special Medical Glue Developed By Mayo Clinic
Rochester, MN (KROC AM News) - A cutting edge medical glue Mayo Clinic helped develop was inspired by barnacles.
According to information on the study that was released by Mayo, researchers "developed a rapid-sealing paste that can stop bleeding organs independent of clotting.”
Mayo has partnered with Massachusetts Institute of Technology in developing the special paste and the two have obtained a patent for the treatment.
Barnacles are sea animals that adhere to rocks, the bottom of ships and large fish with the aim of staying in place despite wet conditions and variable surfaces. They're successful because they exude a type of oil matrix that cleans the surface and repels moisture. Then they follow up with a protein that cross-links them with the molecules of the surface. That two-step process is what happens when the sealing paste is applied to organs or tissues.
Read more about the paste here.
Historically, surgeons would use a type of material that would speed up coagulation and form a clot to stop the bleeding. In the fastest cases, that would still take several minutes. In preclinical studies, this research team has shown the paste to stop bleeding in as little as 15 seconds, even before clotting has begun.
"Our data show how the paste achieves rapid hemostasis in a coagulation-independent fashion. The resulting tissue seal can withstand even high arterial pressures," says Christoph Nabzdyk, M.D., a Mayo Clinic cardiac anesthesiologist and critical care physician. "We think the paste may be useful in stemming severe bleeding, including in internal organs, and in patients with clotting disorders or on blood thinners. This might become useful for the care of military and civilian trauma victims." Nabzdyk is co-senior lead author of the study.
The paste consists of an injectable material that consists of a water-repelling oil matrix and bioadhesive microparticles. It's the microparticles that link to each other and the surface of the tissue after the oil has provided a clean place to connect. The biomaterial slowly resorbs over a period of weeks.
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